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One case report of MRI pigment cirrhosis

sgane,[link widoczny dla zalogowanych], HJV), homozygous Cys282Tyr in 310 patients in 9 patients with the wrong intention mutations associated with HJr , 8 cases of iron -related parameters were significantly higher than that of gender,[link widoczny dla zalogowanych], age is not matched with HJV mutations Cys282Tyr homozygous I patients with primary Hemochromatosis clinical manifestations of common skin pigmentation , cirrhosis ,[link widoczny dla zalogowanych], diabetes,[link widoczny dla zalogowanych], primary liver cancer , abdominal pain , endocrine disorders , heart disease, joint disease ,[link widoczny dla zalogowanych], neurological symptoms . 84 patients with a l0o% pigmentation of the 25- 40% of the first performance; liver involvement often the first organ was chronic, mostly normal liver function ; until the later stages of liver function was impaired only when significant Symptoms. Primary hemochromatosis often lack a significant hepatic necrosis and inflammation , the occurrence of fibrosis. Excessive iron deposition , can stimulate collagen synthesis. Cirrhosis patients , 9O% enlargement of the liver in patients over the left lobe more than the right lobe of the invasion , liver , hard texture, no tenderness , the surface smooth or palpable nodules , edge sharp. Normal liver tissue per gram of iron is less than 250ug. When iron per gram liver tissue when greater than lmg , MRI abnormalities only . Bad because the paramagnetic effect of iron to liver 1rI and relaxation time shortened, the shortening is the l5 times Tl , the results of its comprehensive use of existing sequences Tl and T2 weighted imaging, excessive siderosis of the liver signal intensity was Reduced, especially in gradient echo and spin-echo weighted images signal intensity close to background noise l. 【
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