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Chongqing survey cytomegalovirus infection blood donors

The highest positive rate was 32.7% , but each between the two groups were not statistically significant difference , Table 2. Bad 2 CMV-IgM antibodies in blood donors positive relationship between age and rate of exchange of experience 3 Discussion 351 CMV infection in immunocompromised populations can lead to increased patient morbidity and mortality , and transfusion transmitted CMV is the main way of First, effective preventive measures is to provide patients with CMV -negative blood L1], such as the method to filter out white blood cells to prevent the spread of CMV L5], but such methods are inadequate to completely prevent CMV transmission level. Helinx recently developed technology ( a photosensitizer long wave ultraviolet light technology) used to inactivate platelets CMV, and success in animal studies , the clinical promise for l , l so as to provide clinical CMV -negative blood products in patients with L2 ]. Currently, the clinical use of ELISA detection of CMV -specific multi- IgM,[link widoczny dla zalogowanych], as proven acute CMV infection. It is reported that CMV infection in the normal population up to 5O ~ 9OL1]. The experimental results show that Chongqing CMV-IgM antibodies in blood donors positive rate is low ( 18%) , females than males. It is believed that ,[link widoczny dla zalogowanych], CMV organ transplantation , immune function ,[link widoczny dla zalogowanych], and fetal defects such persons is an important source of the disease , blood CMV-IgM antibodies appear early in the peak of viral infection . With the peak of the past, although the body has excreted CMV ,[link widoczny dla zalogowanych], but CMV-IgM may be negative. CMV-IgM detection suggest that infection in the active phase , but not serum CMV-IgM detection can not exclude the primary or secondary infection or the presence of active infection _1 ]. Therefore ,[link widoczny dla zalogowanych], excluding the existing Method CMV in the blood and can not EIISA as well, available PCR detection methods such as the right to improve the safety of blood transfusion Ⅲ.