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Sheep placental preparations on mice immune function and hypoxia tolerance of

Agent x44,[link widoczny dla zalogowanych], rats sodium nitrite poisoning and acute cerebral hypoxia survival time (n = 10,[link widoczny dla zalogowanych],4 -) Tab2Effectsofgoatplacentalpreparationsonthesodiumnitritepoisonousandacutecerebralanoxiainmice (n = 10.i4-5) compared with the month:. P <0. Ol, P <0.05Comparedwiththecontrolgroup: P <0O1. P <005 agents on the immune organs of mice with weight gain, their body's immune function enhancement. The possible mechanism is that some active ingredients of the preparation (such as: glycosphingolipids) can promote the proliferation of lymphocytes in thymus and spleen, improve the B, T lymphocyte activity and antibody production capacity, even with a raise of their immune force components (such as: gamma globulin), increase immunity is the combined result of active substances. Delayed hypersensitivity, also known as type Ⅳ allergic reaction, mainly mediated by the participation of T lymphocytes, but also reflect the body's immune function in a specific key indicators. In this experiment, low and medium dose groups of mice ear weight compared with the control group difference was not significant, but the high dose group achieved a significant level, and with the dose increased ear weight difference there is an increasing trend, as dose The existence dependency also needs to be confirmed by further studies. Sodium nitrite can normal hemoglobin ferrous iron into ferric hemoglobin, hemoglobin oxygen carrying capacity of destruction, causing death of tissue hypoxia. Test of acute cerebral hypoxia may reflect the tested samples of cerebral ischemia and the protective effect of hypoxia on the body tissue oxygen utilization. Survival trial of sodium nitrite poisoning, although the middle dose group, survival time compared with the control group was not significant, but the 3 dose groups compared with the control group was significantly prolonged the survival time of hypoxia; acute cerebral ischemia test 3 The survival time of treated groups compared with the control group the differences were significant, and survival time was longer with the increasing dose trend. The results showed that sheep placental preparations in mice by increasing the body's oxygen utilization, reduces brain oxygen levels to achieve its improved hypoxia tolerance in mice and enhancement of mouse anti-stress effect of hypoxia. According to the Acknowledgements: The help in this experiment the learning Haitao, Li Feng silver students to express my sincere thanks!