www.public4you.fora.pl

njlpkhgea

,[link widoczny dla zalogowanych]
Vascular endothelial growth factor,[link widoczny dla zalogowanych], γ interferon and nitric oxide plasma levels and diabetic retinopathy

. VEGF,[link widoczny dla zalogowanych], IFN-double-antibody sandwich ELISA method, NO is spectrophotometry. Assay by the United States and Biological Engineering Co.,[link widoczny dla zalogowanych], Ltd. Shenzhen Crystal available. The U.S. company Bio-Rad enzyme-linked analyzer Coda = 3. Statistical analysis: results to ± said. Significant test and by linear correlation analysis. Second, the results compared with the control group I, NDR and DR groups VEGF and NO were significantly increased in the ancient; DR group was significantly higher than the NDR group VEGF,[link widoczny dla zalogowanych], IFN-and NO were significantly lower than the NDR group. A significant difference (P <0.05; P <0O1; P <005) (Table 1). Table I in each group VEGF, IFN a, NO content in comparison (; ±) depression: comparison with the control larvae. 'P <005. ¨ P <001; and jade retinopathy group. P <005P <0.012 correlation test showed that, NDR group of VEGF and NO content was linear correlation (r = 0.30P <0.05). There was no correlation between the other groups. Author: 250031, Jinan, Jinan Military General Hospital, KFOR seized (Luo Nanping, Yang truth, the margin of the military), ophthalmology (thick yellow bin); the First People's Hospital of Lianyungang City (Liu Zhonglun) * Clinical study of the discussions of this study were 74 patients with DM DR who happened to 4l cases, accounting for 55.4% VEGF levels in patients with progressive increase in DR and ultra-expression, suggesting that VEGF is the formation of blood vessels in the eye of the important factors in disease, pathogenic mechanisms of DM may be under, the retina ischemia and hypoxia, VEGF produced a large number of eyes with endothelial cell surface high-affinity receptor-mediated binding to vascular endothelial proliferation, leading to the formation of new blood vessels. The results showed that, IFN an ancient volume increased with the increasing of VEGF, the endothelial cells and vascular basement membrane damage, prompting a cell proliferation IFN enhanced content increased, with the progression of the disease, DR and other factors of immunity in the body effect of IFN a pair of cell proliferation decreased, resulting in IFN-VEGF and other growth factors on the antagonism of imbalance, IFN a reduction in the level, and very significant increase in VEGF is, IFN can not effectively contain a VEGF and other retinal capillary vascular proliferation, disease progression is caused by deterioration of DR patients an important factor. NO than normal in patients with higher NDR is very significant. NDR group, NO increased VEGF was positive correlation, suggesting that the process in the DR, VEGF and other cytokines in a large number of co-stimulation with LPS produce high concentrations of NO, and NO is the vascular endothelial cell injury in terminal effect factor, the trial DR NO levels were significantly lower in patients with NDR group, indicating increased NO in the DM early and late NO decreased. In the DR hemodynamic changes and cell components, while reducing the release of NO synthesis, and its increased vasodilatation decreased microcirculation, neovascularization in patients with DR is the key.