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Limbal stem cell transplantation for recurrent pterygium

In addition to adding limbal stem cell transplantation. Either surgical methods, have the possibility of recurrence after surgery. According to the literature, the recurrence rate after pterygium surgery abroad is 20% to 70%, domestic 24% to 89%. In general, the initial issuance of the recurrence rate of pterygium surgery lower reoperation for recurrent pterygium recurrence rate is higher. Because of recurrent pterygium and the cornea and sclera under severe adhesions, which adhesions can even be deep corneal stroma invasion and, in addition to loss of recurrent pterygium pterygium onset of the structural characteristics of head, neck, three-part body boundaries are not easily distinguishable, some patients may also be thinning the sclera. Inexperienced doctors may be possible for the removal of the eye caused by a clean puncture. Thus the re-recurrent pterygium surgery is a very difficult problem. In addition to the recurrence of pterygium and Individual Differences, surgical resection is complete, whether it is reasonable perioperative and postoperative medication to stimulate it to eliminate 906 • For outside, there is evidence that it also with limbal stem cell dysfunction in close related. Routine pterygium resection line could be considered to form part of the cornea and partial loss of the limbal stem cell deficiency]. Using stem cell transplantation, not only for the lesion to provide a healthy limbal epithelial origin, so that normal corneal transparency at the same time, which contain stem cells, limbal tissue can form a subcutaneous tissue of the cornea to the corneal growth], effectively avoiding the recurrence of pterygium. To ensure the operation is successful, on the following points must be considered seriously: (1) need for recurrent pterygium surgery again, after the initial surgery must be at least 6 months, and so completely still inflammation behind the possible re-operation, otherwise, re-operation can lead to more serious scar. (2) surgery should be carried out under the operating microscope, because only under a microscope in order to reduce damage to the surgery to better discern the various organizations and removal of pterygium. (3) organization pterygium excision should be clean, but not cut too deeply. Pathology showed that the growth of pterygium and corneal invasion generally elastic layer. Therefore, ablation should not hurt the corneal stroma, especially in the limbal epithelium obtained when the depth of no more than before the elastic layer, otherwise, will inevitably produce corneal scar. (4) in the pterygium excision while minimizing damage to healthy limbus, the best range of less than 1 / 4 circle. (5) should be taken to avoid graft to the limbal stem cells get too deep or too much on the corneal injury, causing corneal defects, corneal decompensation caused by disease or the formation of a new pseudo-pterygium. (6) should be locally administered after a powerful anti-inflammatory drugs, in order to minimize the inflammatory response
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